Incidence & Distribution of Sanfilippo Syndrome
MPS III is the most common type of Mucopolysaccharidosis; the estimated incidence of all four subtypes combined is 1 in 70,000 newborns.
By Type of Sanfilippo
| Type | Incidence in Thousands# | Prevalence in Thousands* | Carrier Frequency |
|---|---|---|---|
| Type A | 128 | 114 | 169 |
| Type B | 235 | 211 | 230 |
| Type C | 1407 | 1407 | 593 |
| Type D | 1056 | 1056 | 514 |
Source: Meikle PJ, Hopwood JJ, Clague AE, Carey WF (January 1999). “Prevalence of lysosomal storage disorders”. JAMA. 281 (3): 249–54. doi:10.1001/jama.281.3.249. PMID 9918480. https://pubmed.ncbi.nlm.nih.gov/9918480/
Factors in Sanfilippo
Sanfilippo Syndrome appears to affect every gender, nationality, socio-economic bracket, and geographic region.
Co-occurring Conditions
Children with Sanfilippo Syndrome are also often diagnosed with Autism.