Midlands Gives 2021 is an annual online giving challenge hosted by the Central Carolina Community Foundation that brings the region together as one community, raising money and awareness for local nonprofits.

Cure Sanfilippo Foundation is among the many Columbia-based organizations participating in Midlands Gives 2021. Additionally, several families with children that have Sanfilippo live or used to live in the Midland region, including Keira, Paisleigh, Eliza, Everett, and Rowen.